The Microrna Cluster Mir 106b~25 Regulates Adult Neural

The MicroRNA Cluster miR-106b~25 Regulates Adult Neural.

11/02/2015 · The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation Jamie O. Brett, 1 Valérie M. Renault, 1 Victoria A. Rafalski, 1, 2 Ashley E. Webb, 1 and Anne Brunet 1, 2. The MicroRNA Cluster miR-106b~25 Regulates Adult Neural Stem/Progenitor Cell Proliferation and Neuronal Differentiation Jamie O. Brett 1, Valérie M. Renault 1, Victoria A. Rafalski 1,2, Ashley E. Webb 1, Anne Brunet 1,2.

Controlling adult NSC number and function is fundamental for preserving the stem cell pool and ensuring proper levels of neurogenesis throughout life. Here we study the importance of the microRNA gene cluster miR-106b~25 miR-106b, miR-93, and miR-25 in primary cultures of neural stem/progenitor cells NSPCs isolated from adult mice. We find. 01/02/2011 · miR-106b, miR-93, and miR-25 are expressed in adult NSPC cultures. We examined the expression levels of the miR-106b~25 cluster members miR-106b, miR-93, and miR-25; Figure 1A in self-renewing or differentiating NSPCs isolated from young adult 3 month-old mice. Controlling adult NSC number and function is fundamental for preserving the stem cell pool and ensuring proper levels of neurogenesis throughout life. Here we study the importance of the microRNA gene cluster miR-106b~25 miR-106b, miR-93, and miR-25 in primary cultures of neural stem/progenitor cells NSPCs isolated from adult mice. Sigma-Aldrich offers abstracts and full-text articles by [Jamie O Brett, Valérie M Renault, Victoria A Rafalski, Ashley E Webb, Anne Brunet].

26/09/2017 · Here we study the importance of the microRNA gene cluster miR-106b~25 miR-106b, miR-93, and miR-25 in primary cultures of neural stem/progenitor cells NSPCs isolated from adult mice. We find that knocking down miR-25 decreases NSPC proliferation, whereas ectopically expressing miR-25 promotes NSPC proliferation. Controlling adult NSC number and function is fundamental for preserving the stem cell pool and ensuring proper levels of neurogenesis throughout life. Here we study the importance of the microRNA gene cluster miR‐ 106b~25 miR‐106b, miR‐93, and miR‐25 in primary cultures of neural stem/progenitor cells NSPCs isolated from adult mice. The microRNA cluster miR-106-25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation.pdf Available via license: CC BY 2.5 Content may be subject to copyright. 30/03/2016 · The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. Aging. 2011; 3:108–124. [PMC free article] Kan T, Sato F, Ito T, Matsumura N, David S, et al. The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim.

17/04/2018 · The miR-106b-25 cluster mediates breast tumor initiation through. Aung MO, Wasser S, Lim SG, et al. Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma. Cancer Sci. Rafalski VA, Webb AE, Brunet A. The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal. 18/02/2013 · MicroRNA-106b∼25 regulates apoptosis of bone marrow-derived stromal cells. The miR-106b∼25 cluster has been previously shown to regulate apoptosis in cancer cells. 14 That finding prompted us to examine the effect of miR-106b∼25 deletion on. In NSPCs isolated from adult mice, the expression of miR-106b–25 clusters has been identified. The overexpression of miR-25 or the entire miR-106b–25 cluster promotes adult NSPC proliferation and neuronal differentiation Brett et al., 2011. The potential targets of miR-25 are involved in the TGFβ and insulin/IGF signaling pathways.

microRNA cluster miR‐106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. Aging. 2011; 3: 108‐124. 2. Kan T, Sato F, Ito T, Matsumura N, David S, et al. The miR‐ 106b‐25 polycistron, activated by genomic amplification. AimsMicroRNAs miRNAs, miR are endogenous short RNA sequences that regulate a wide range of physiological and pathophysiological processes. Several miRNAs control the formation o. In molecular biology mir-25 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. mir-25 levels increase in human heart failure, and treatment with an anti-sense RNA molecule antagomiR was recently reported to halt disease progression and improves cardiac function in a. Holiday Schedule: Addgene will be closed November 28th & 29th for the Thanksgiving holiday. Order processing and shipping may be delayed the week of November 25th - 29th.

22/10/2015 · Summary. Neural stem cells NSCs proliferation can be influenced by repetitive transcranial magnetic stimulation rTMS in vivo via microRNA-106b-25 cluster, but the underlying mechanisms are poorly understood.

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